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Chemical structure of Revefenacin

GC31761

Revefenacin

Also listed as Revefenacin (TD-4208)

Revefenacin (TD-4208) (TD-4208; GSK1160724) is a potent mAChR antagonist; has a high affinity on M3 receptor with a Ki of 0·18 nM

ChemicalCAS864750-70-9MW597.75FormulaC35H43N5O4
CAS number
864750-70-9
Molecular weight
597.75
Formula
C35H43N5O4
Solubility
DMSO : ≥ 125 mg/mL (209·12 mM)
InChIKey
FYDWDCIFZSGNBU-UHFFFAOYSA-N
Catalogue number
GC31761
Brand
GLPBIO
Computed properties PubChem CID 11753673 · XLogP 4.1 · TPSA 108 Ų · H-bond donors 2
XLogP
4.1
TPSA
108 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
11
Heavy atoms
44

SMILES CN(CCN1CCC(CC1)OC(=O)NC2=CC=CC=C2C3=CC=CC=C3)C(=O)C4=CC=C(C=C4)CN5CCC(CC5)C(=O)N

Computed descriptors from PubChem (CID 11753673), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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