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Chemical structure of BMS-935177

GC31760

BMS-935177

Also known as 7-(2-hydroxypropan-2-yl)-4-[2-methyl-3-(4-oxoquinazolin-3-yl)phenyl]-9H-carbazole-1-carboxamide

BMS-935177 is a potent and selective reversible inhibitor of Bruton’s tyrosine kinase (Btk) with an IC50 of 3 nM

ChemicalCAS1231889-53-4MW502.56FormulaC31H26N4O3
CAS number
1231889-53-4
Molecular weight
502.56
Formula
C31H26N4O3
Solubility
DMSO ： ≥ 130 mg/mL (258·68 mM)
InChIKey
TVJRDCQUZMGBAB-UHFFFAOYSA-N
Catalogue number
GC31760
Brand
GLPBIO
Computed properties PubChem CID 70647728 · XLogP 4.5 · TPSA 112 Ų · H-bond donors 3
XLogP
4.5
TPSA
112 Ų
H-bond donors
3
H-bond acceptors
4
Rotatable bonds
4
Heavy atoms
38

SMILES CC1=C(C=CC=C1N2C=NC3=CC=CC=C3C2=O)C4=C5C6=C(C=C(C=C6)C(C)(C)O)NC5=C(C=C4)C(=O)N

Computed descriptors from PubChem (CID 70647728), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.