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Chemical structure of CCR2-RA-[R]

GC31714

CCR2-RA-[R]

Also known as (2R)-3-acetyl-1-(4-chloro-2-fluorophenyl)-2-cyclohexyl-4-hydroxy-2H-pyrrol-5-one

CCR2-RA -[R] can inhibit CCR2 in a non-competitive binding manner, mainly by blocking activation-related conformational changes and the formation of G-protein binding interfaces

ChemicalCAS512177-83-2MW351.8FormulaC18H19ClFNO3
CAS number
512177-83-2
Molecular weight
351.8
Formula
C18H19ClFNO3
Solubility
DMSO : ≥ 125 mg/mL (355·32 mM);Water : < 0·1 mg/mL (insoluble)
InChIKey
VQNLJXWZGVRLBA-MRXNPFEDSA-N
Catalogue number
GC31714
Brand
GLPBIO
Computed properties PubChem CID 12093170 · XLogP 4.3 · TPSA 57.6 Ų · H-bond donors 1
XLogP
4.3
TPSA
57.6 Ų
H-bond donors
1
H-bond acceptors
4
Rotatable bonds
3
Heavy atoms
24

SMILES CC(=O)C1=C(C(=O)N([C@@H]1C2CCCCC2)C3=C(C=C(C=C3)Cl)F)O

Computed descriptors from PubChem (CID 12093170), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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