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Chemical structure of Fiboflapon

GC31689

Fiboflapon

Also listed as Fiboflapon (GSK2190915)

Fiboflapon (GSK2190915) (GSK2190915; AM-803) is a potent and orally bioavailable 5-lipoxygenase-activating protein (FLAP) inhibitor with a potency of 2·9 nM in FLAP binding, an IC50 of 76 nM for inhibition of LTB4 in human blood

ChemicalCAS936350-00-4MW637.83FormulaC38H43N3O4S
CAS number
936350-00-4
Molecular weight
637.83
Formula
C38H43N3O4S
Solubility
DMSO : 50 mg/mL (78·39 mM);Water : < 0·1 mg/mL (insoluble)
InChIKey
DFQGDHBGRSTTHX-UHFFFAOYSA-N
Catalogue number
GC31689
Brand
GLPBIO
Computed properties PubChem CID 44473151 · XLogP 7.8 · TPSA 112 Ų · H-bond donors 1
XLogP
7.8
TPSA
112 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
13
Heavy atoms
46

SMILES CCOC1=NC=C(C=C1)C2=CC=C(C=C2)CN3C4=C(C=C(C=C4)OCC5=NC=C(C=C5)C)C(=C3CC(C)(C)C(=O)O)SC(C)(C)C

Computed descriptors from PubChem (CID 44473151), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.