Loading...
Chemical structure of TYK2-IN-2

GC31668

TYK2-IN-2

Also known as 6-(3,5-dimethylanilino)-8-(methylamino)imidazo[1,2-b]pyridazine-3-carboxamide

TyK2-IN-2 (Compoud 18) is a potent and selective TYK2 inhibitor with IC50s of 7 nM, 0·1 μM and 0·05 μM for TYK2 JH2, IL-23 and IFNα, respectively

ChemicalCAS2098466-94-3MW310.35FormulaC16H18N6O
CAS number
2098466-94-3
Molecular weight
310.35
Formula
C16H18N6O
Solubility
DMSO ： ≥ 25 mg/mL (80·55 mM)
InChIKey
SNVFFECYFQEWTL-UHFFFAOYSA-N
Catalogue number
GC31668
Brand
GLPBIO
Computed properties PubChem CID 129626433 · XLogP 2.1 · TPSA 97.3 Ų · H-bond donors 3
XLogP
2.1
TPSA
97.3 Ų
H-bond donors
3
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
23

SMILES CC1=CC(=CC(=C1)NC2=NN3C(=CN=C3C(=C2)NC)C(=O)N)C

Computed descriptors from PubChem (CID 129626433), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.