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Chemical structure of Lorecivivint

GC31663

Lorecivivint

Also listed as Adavivint (SM04690)

Adavivint (SM04690) (SM04690; Lorecivivint) is a potent and selective inhibitor of canonical Wnt signaling, with an EC50 of 19·5 nM via a high-throughput TCF/LEF-reporter assay in SW480 colon cancer cells

ChemicalCAS1467093-03-3MW505.55FormulaC29H24FN7O
CAS number
1467093-03-3
Molecular weight
505.55
Formula
C29H24FN7O
Solubility
DMSO : 25 mg/mL (49·45 mM)
InChIKey
AQDWDWAYVBQMAM-UHFFFAOYSA-N
Catalogue number
GC31663
Brand
GLPBIO
Computed properties PubChem CID 135565709 · XLogP 4.5 · TPSA 112 Ų · H-bond donors 3
XLogP
4.5
TPSA
112 Ų
H-bond donors
3
H-bond acceptors
6
Rotatable bonds
6
Heavy atoms
38

SMILES CC(C)CC(=O)NC1=CN=CC(=C1)C2=CC3=C(C=C2)NN=C3C4=NC5=C(N4)C=NC=C5C6=CC(=CC=C6)F

Computed descriptors from PubChem (CID 135565709), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.