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Chemical structure of MCC950 (CP-456773)

GC31644

MCC950 (CP-456773)

Also known as 1-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-3-[4-(2-hydroxypropan-2-yl)furan-2-yl]sulfonylurea

MCC950 (CP-456773) (CP-456773; CRID3) is a potent and selective NLRP3 inhibitor with IC50s of 7·5 and 8·1 nM in BMDMs and HMDMs, respectively

ChemicalCAS210826-40-7MW404.48FormulaC20H24N2O5S
CAS number
210826-40-7
Molecular weight
404.48
Formula
C20H24N2O5S
Solubility
DMSO ： ≥ 28 mg/mL (69·22 mM)
InChIKey
HUUSXLKCTQDPGL-UHFFFAOYSA-N
Catalogue number
GC31644
Brand
GLPBIO
Computed properties PubChem CID 9910393 · XLogP 3.4 · TPSA 117 Ų · H-bond donors 3
XLogP
3.4
TPSA
117 Ų
H-bond donors
3
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
28

SMILES CC(C)(C1=COC(=C1)S(=O)(=O)NC(=O)NC2=C3CCCC3=CC4=C2CCC4)O

Computed descriptors from PubChem (CID 9910393), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.