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Chemical structure of AVE5688

GC31627

AVE5688

Also known as 4-[(2-chloro-4,5-difluorobenzoyl)carbamoylamino]-3-(trifluoromethoxy)benzoic acid

AVE5688 is an inhibitor of glycogen phosphorylase (GP), with IC50s of 430 nM and 915 nM and Kds of 170 nM and 530 nM for rabbit muscle glycogen phosphorylase (rmGPb and rmGPa, respectively); AVE5688 can be used for the research of type 2 diabetes

ChemicalCAS613260-13-2MW438.69FormulaC16H8ClF5N2O5
CAS number
613260-13-2
Molecular weight
438.69
Formula
C16H8ClF5N2O5
Solubility
DMSO ： 100 mg/mL (227·95 mM; Need ultrasonic)
InChIKey
NWQGDIBCFLDHDO-UHFFFAOYSA-N
Catalogue number
GC31627
Brand
GLPBIO
Computed properties PubChem CID 16070039 · XLogP 4.5 · TPSA 105 Ų · H-bond donors 3
XLogP
4.5
TPSA
105 Ų
H-bond donors
3
H-bond acceptors
10
Rotatable bonds
4
Heavy atoms
29

SMILES C1=CC(=C(C=C1C(=O)O)OC(F)(F)F)NC(=O)NC(=O)C2=CC(=C(C=C2Cl)F)F

Computed descriptors from PubChem (CID 16070039), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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