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Chemical structure of FK-448 Free base

GC31563

FK-448 Free base

Also known as [4-(4-propan-2-ylpiperazine-1-carbonyl)phenyl] 1,2,3,4-tetrahydronaphthalene-1-carboxylate

FK-448 Free base is an effective and specific inhibitor of chymotrypsin, with an IC50 of 720 nM

ChemicalCAS85858-76-0MW406.52FormulaC25H30N2O3
CAS number
85858-76-0
Molecular weight
406.52
Formula
C25H30N2O3
Solubility
Soluble in DMSO
InChIKey
BPNWUGVANKCJDV-UHFFFAOYSA-N
Catalogue number
GC31563
Brand
GLPBIO
Computed properties PubChem CID 174764 · XLogP 4.3 · TPSA 49.9 Ų · H-bond donors 0
XLogP
4.3
TPSA
49.9 Ų
H-bond donors
0
H-bond acceptors
4
Rotatable bonds
5
Heavy atoms
30

SMILES CC(C)N1CCN(CC1)C(=O)C2=CC=C(C=C2)OC(=O)C3CCCC4=CC=CC=C34

Computed descriptors from PubChem (CID 174764), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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