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Chemical structure of Fidarestat

GC31487

Fidarestat

Also listed as Fidarestat (SNK 860)

Fidarestat (SNK 860) (SNK 860) is an inhibitor of aldose reductase, with IC50s of 26 nM, 33 μM, and 1·8 μM for aldose reductase, AKR1B10 and V301L AKR1B10, respectively; Fidarestat (SNK 860) (SNK 860) has the potential to treat diabetic disease

ChemicalCAS136087-85-9MW279.22FormulaC12H10FN3O4
CAS number
136087-85-9
Molecular weight
279.22
Formula
C12H10FN3O4
Solubility
DMSO: 250 mg/mL (895·35 mM)
InChIKey
WAAPEIZFCHNLKK-UFBFGSQYSA-N
Catalogue number
GC31487
Brand
GLPBIO
Computed properties PubChem CID 160024 · XLogP -0.3 · TPSA 111 Ų · H-bond donors 3
XLogP
-0.3
TPSA
111 Ų
H-bond donors
3
H-bond acceptors
5
Rotatable bonds
1
Heavy atoms
20

SMILES C1[C@H](OC2=C([C@]13C(=O)NC(=O)N3)C=C(C=C2)F)C(=O)N

Computed descriptors from PubChem (CID 160024), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
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