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Chemical structure of FCE 28654

GC31384

FCE 28654

Also known as [4-[(4R,5R)-2-[[[2,6-di(propan-2-yl)phenyl]carbamoylamino]methyl]-4,5-dimethyl-1,3-dioxolan-2-yl]phenyl] dihydrogen phosphate

FCE 28654 is an inhibitor of acylCoA: cholesterol acyltransferase (ACAT), weakly inhibiting ACAT in microsomes from rabbit aorta and intestine, and monkey liver, with IC50s of 2·55, 1·08 and 5·69 μM, respcetively

ChemicalCAS169474-77-5MW506.53FormulaC25H35N2O7P
CAS number
169474-77-5
Molecular weight
506.53
Formula
C25H35N2O7P
Solubility
Soluble in DMSO
InChIKey
WUEHURHTEPWPPO-QZTJIDSGSA-N
Catalogue number
GC31384
Brand
GLPBIO
Computed properties PubChem CID 9935980 · XLogP 3.3 · TPSA 126 Ų · H-bond donors 4
XLogP
3.3
TPSA
126 Ų
H-bond donors
4
H-bond acceptors
7
Rotatable bonds
8
Heavy atoms
35

SMILES C[C@@H]1[C@H](OC(O1)(CNC(=O)NC2=C(C=CC=C2C(C)C)C(C)C)C3=CC=C(C=C3)OP(=O)(O)O)C

Computed descriptors from PubChem (CID 9935980), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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