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Chemical structure of Dermorphin

GC31168

Dermorphin

Also known as (2S)-N-[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]-1-[(2S)-2-[[2-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-3-phenylpropanoyl]amino]acetyl]amino]-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carboxamide

Dermorphin is a natural heptapeptide μ-opioid receptor (MOR) agonist found in amphibian skin

ChemicalCAS77614-16-5MW802.87FormulaC40H50N8O10
CAS number
77614-16-5
Molecular weight
802.87
Formula
C40H50N8O10
Solubility
H2O : 120 mg/mL (149·46 mM; Need ultrasonic)
InChIKey
FHZPGIUBXYVUOY-VWGYHWLBSA-N
Catalogue number
GC31168
Brand
GLPBIO
Computed properties PubChem CID 5485199 · XLogP 0 · TPSA 296 Ų · H-bond donors 10
XLogP
0
TPSA
296 Ų
H-bond donors
10
H-bond acceptors
11
Rotatable bonds
19
Heavy atoms
58

SMILES C[C@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NCC(=O)N[C@@H](CC2=CC=C(C=C2)O)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CO)C(=O)N)NC(=O)[C@H](CC4=CC=C(C=C4)O)N

Computed descriptors from PubChem (CID 5485199), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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