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Chemical structure of CE-224535 (PF-04905428)

GC31157

CE-224535 (PF-04905428)

Also known as 2-chloro-N-[(1-hydroxycycloheptyl)methyl]-5-[4-[(2R)-2-hydroxy-3-methoxypropyl]-3,5-dioxo-1,2,4-triazin-2-yl]benzamide

CE-224535 (PF-04905428) is a selective P2X7 receptor antagonist

ChemicalCAS724424-43-5MW480.94FormulaC22H29ClN4O6
CAS number
724424-43-5
Molecular weight
480.94
Formula
C22H29ClN4O6
Solubility
DMSO : 100 mg/mL (207·93 mM; Need ultrasonic)
InChIKey
FUCKCIVGBCBZNP-MRXNPFEDSA-N
Catalogue number
GC31157
Brand
GLPBIO
Computed properties PubChem CID 11547499 · XLogP 1.6 · TPSA 132 Ų · H-bond donors 3
XLogP
1.6
TPSA
132 Ų
H-bond donors
3
H-bond acceptors
7
Rotatable bonds
8
Heavy atoms
33

SMILES COC[C@@H](CN1C(=O)C=NN(C1=O)C2=CC(=C(C=C2)Cl)C(=O)NCC3(CCCCCC3)O)O

Computed descriptors from PubChem (CID 11547499), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.