GC31141
Antihistamine-1
Also known as 1-[(4-fluorophenyl)methyl]-2-[4-(4-methylpyrazol-1-yl)piperidin-1-yl]benzimidazole
Antihistamine-1 is a H1-antihistamine (Ki=6·9 nM) with acceptable blood-brain barrier penetration and also an inhibitor of CYP2D6 and hERG channel with IC50s of 5·4 and 0·8 μM, respectively
ChemicalCAS1186430-60-3MW389.47FormulaC23H24FN5
- CAS number
- 1186430-60-3
- Molecular weight
- 389.47
- Formula
- C23H24FN5
- Solubility
- Soluble in DMSO
- InChIKey
- YGQQBKYVKLZEMA-UHFFFAOYSA-N
- Catalogue number
- GC31141
- Brand
- GLPBIO
Computed properties PubChem CID 45272895 · XLogP 4.4 · TPSA 38.9 Ų · H-bond donors 0
- XLogP
- 4.4
- TPSA
- 38.9 Ų
- H-bond donors
- 0
- H-bond acceptors
- 4
- Rotatable bonds
- 4
- Heavy atoms
- 29
SMILES CC1=CN(N=C1)C2CCN(CC2)C3=NC4=CC=CC=C4N3CC5=CC=C(C=C5)F
Computed descriptors from PubChem (CID 45272895), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il