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Chemical structure of Tilapertin (AMG747)

GC31115

Tilapertin (AMG747)

Also known as 2-[4-[(R)-phenyl-[3-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]acetic acid

Tilapertin (AMG747) is an oral inhibitor of glycine transporter type-1 (GlyT1)

ChemicalCAS1000690-85-6MW378.39FormulaC20H21F3N2O2
CAS number
1000690-85-6
Molecular weight
378.39
Formula
C20H21F3N2O2
Solubility
Soluble in DMSO
InChIKey
MDLQJNCGZVDZFV-LJQANCHMSA-N
Catalogue number
GC31115
Brand
GLPBIO
Computed properties PubChem CID 25063875 · XLogP 1.5 · TPSA 43.8 Ų · H-bond donors 1
XLogP
1.5
TPSA
43.8 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
5
Heavy atoms
27

SMILES C1CN(CCN1CC(=O)O)[C@H](C2=CC=CC=C2)C3=CC(=CC=C3)C(F)(F)F

Computed descriptors from PubChem (CID 25063875), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Pricing
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