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Chemical structure of PH-064 (BIM-46187)

GC31051

PH-064 (BIM-46187)

Also known as (2R)-2-amino-3-[[(2R)-2-amino-3-[(8S)-8-(cyclohexylmethyl)-2-phenyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-7-yl]-3-oxopropyl]disulfanyl]-1-[(8S)-8-(cyclohexylmethyl)-2-phenyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-7-yl]propan-1-one

PH-064 (BIM-46187) (BIM-46187) is an inhibitor of heterotrimeric G-protein complex

ChemicalCAS892546-37-1MW795.11FormulaC44H58N8O2S2
CAS number
892546-37-1
Molecular weight
795.11
Formula
C44H58N8O2S2
Solubility
DMSO : 100 mg/mL (125·77 mM; Need ultrasonic)
InChIKey
GGDNOAWICIHSAW-KEAHXZLPSA-N
Catalogue number
GC31051
Brand
GLPBIO
Computed properties PubChem CID 11593027 · XLogP 6.4 · TPSA 179 Ų · H-bond donors 2
XLogP
6.4
TPSA
179 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
13
Heavy atoms
56

SMILES C1CCC(CC1)C[C@H]2C3=NC(=CN3CCN2C(=O)[C@H](CSSC[C@@H](C(=O)N4CCN5C=C(N=C5[C@@H]4CC6CCCCC6)C7=CC=CC=C7)N)N)C8=CC=CC=C8

Computed descriptors from PubChem (CID 11593027), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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