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Chemical structure of AM-2099

GC30917

AM-2099

Also known as 4-[2-methoxy-4-(trifluoromethyl)phenyl]-N-(1,3-thiazol-2-yl)quinazoline-7-sulfonamide

AM-2099 is a potent and selective inhibitor of voltage-gated sodium channel Nav1·7 with an IC50 of 0·16 μM for human Nav1·7

ChemicalCAS1443373-17-8MW466.46FormulaC19H13F3N4O3S2
CAS number
1443373-17-8
Molecular weight
466.46
Formula
C19H13F3N4O3S2
Solubility
DMSO : ≥ 150 mg/mL (321·57 mM)
InChIKey
VSUDRCZPHWUXEW-UHFFFAOYSA-N
Catalogue number
GC30917
Brand
GLPBIO
Computed properties PubChem CID 86687532 · XLogP 3.9 · TPSA 131 Ų · H-bond donors 1
XLogP
3.9
TPSA
131 Ų
H-bond donors
1
H-bond acceptors
11
Rotatable bonds
5
Heavy atoms
31

SMILES COC1=C(C=CC(=C1)C(F)(F)F)C2=NC=NC3=C2C=CC(=C3)S(=O)(=O)NC4=NC=CS4

Computed descriptors from PubChem (CID 86687532), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.