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Chemical structure of HC-070

GC30799

HC-070

Also known as 8-(3-chlorophenoxy)-7-[(4-chlorophenyl)methyl]-1-(3-hydroxypropyl)-3-methylpurine-2,6-dione

HC-070 is an antagonist of TRPC4/TRPC5, with IC50s of 9·3 nM and 46 nM for hTRPC5 and hTRPC4 in cells, respectively

ChemicalCAS1628291-95-1MW475.32FormulaC22H20Cl2N4O4
CAS number
1628291-95-1
Molecular weight
475.32
Formula
C22H20Cl2N4O4
Solubility
DMSO : ≥ 62·5 mg/mL (131·49 mM)
InChIKey
VYJPVPHNGWEIBT-UHFFFAOYSA-N
Catalogue number
GC30799
Brand
GLPBIO
Computed properties PubChem CID 85473309 · XLogP 4 · TPSA 87.9 Ų · H-bond donors 1
XLogP
4
TPSA
87.9 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
7
Heavy atoms
32

SMILES CN1C2=C(C(=O)N(C1=O)CCCO)N(C(=N2)OC3=CC(=CC=C3)Cl)CC4=CC=C(C=C4)Cl

Computed descriptors from PubChem (CID 85473309), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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