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Chemical structure of ADX88178

GC30793

ADX88178

Also known as 5-methyl-N-(4-methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)-1,3-thiazol-2-amine

ADX88178 is a potent metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) with an EC50 of 4 nM for human mGluR4

ChemicalCAS1235318-89-4MW272.33FormulaC12H12N6S
CAS number
1235318-89-4
Molecular weight
272.33
Formula
C12H12N6S
Solubility
DMSO ： ≥ 50 mg/mL (183·60 mM)
InChIKey
MIQNXKWDQRNHAU-UHFFFAOYSA-N
Catalogue number
GC30793
Brand
GLPBIO
Computed properties PubChem CID 46836872 · XLogP 2.2 · TPSA 108 Ų · H-bond donors 2
XLogP
2.2
TPSA
108 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
3
Heavy atoms
19

SMILES CC1=NC(=NC=C1)NC2=NC(=C(S2)C)C3=CNN=C3

Computed descriptors from PubChem (CID 46836872), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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