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Chemical structure of R121919 (NBI30775)

GC30792

R121919 (NBI30775)

Also known as 3-[6-(dimethylamino)-4-methyl-3-pyridinyl]-2,5-dimethyl-N,N-dipropylpyrazolo[1,5-a]pyrimidin-7-amine

R121919 (NBI30775) (NBI30775) is a potent small-molecule CRF1 receptor antagonist with a Ki of 2 to 5 nM for the CRF1 receptor and over 1000-fold weaker activity at the CRF2 receptor, CRF-binding protein, or 70 other receptor types

ChemicalCAS195055-03-9MW380.53FormulaC22H32N6
CAS number
195055-03-9
Molecular weight
380.53
Formula
C22H32N6
Solubility
DMSO ： 6·2 mg/mL (16·29 mM)
InChIKey
ANNRUWYFVIGKHA-UHFFFAOYSA-N
Catalogue number
GC30792
Brand
GLPBIO
Computed properties PubChem CID 9821250 · XLogP 4.7 · TPSA 49.6 Ų · H-bond donors 0
XLogP
4.7
TPSA
49.6 Ų
H-bond donors
0
H-bond acceptors
5
Rotatable bonds
7
Heavy atoms
28

SMILES CCCN(CCC)C1=CC(=NC2=C(C(=NN12)C)C3=CN=C(C=C3C)N(C)C)C

Computed descriptors from PubChem (CID 9821250), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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