Loading...
Chemical structure of LY 178002

GC30610

LY 178002

Also known as (5Z)-5-[(3,5-ditert-butyl-4-hydroxyphenyl)methylidene]-1,3-thiazolidin-4-one

LY 178002 is a potent inhibitor of 5-lipoxygenase (5-LPO), phospholipase A2, with IC50 of 0·6 μM for 5-lipoxygenase, inhibits cellular production of LTB4 by human polymorphonuclear leukocytes, and shows relatively weak inhibition on cyclooxygenase

ChemicalCAS107889-32-7MW319.46FormulaC18H25NO2S
CAS number
107889-32-7
Molecular weight
319.46
Formula
C18H25NO2S
Solubility
Soluble in DMSO
InChIKey
BUDGLLLMROWLOB-ZROIWOOFSA-N
Catalogue number
GC30610
Brand
GLPBIO
Computed properties PubChem CID 6439155 · XLogP 5.2 · TPSA 74.6 Ų · H-bond donors 2
XLogP
5.2
TPSA
74.6 Ų
H-bond donors
2
H-bond acceptors
3
Rotatable bonds
3
Heavy atoms
22

SMILES CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)/C=C\2/C(=O)NCS2

Computed descriptors from PubChem (CID 6439155), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.