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Chemical structure of Acrizanib

GC30242

Acrizanib

Also known as 5-[6-(methylaminomethyl)pyrimidin-4-yl]oxy-N-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]indole-1-carboxamide

Acrizanib (LHA510) is a VEGFR-2 inhibitor, with an IC50 of 17·4 nM for BaF3-VEGFR-2

ChemicalCAS1229453-99-9MW445.4FormulaC20H18F3N7O2
CAS number
1229453-99-9
Molecular weight
445.4
Formula
C20H18F3N7O2
Solubility
DMSO ： 41·67 mg/mL (93·56 mM)
InChIKey
XPIHPLVWOUDMPF-UHFFFAOYSA-N
Catalogue number
GC30242
Brand
GLPBIO
Computed properties PubChem CID 59394698 · XLogP 2.4 · TPSA 98.9 Ų · H-bond donors 2
XLogP
2.4
TPSA
98.9 Ų
H-bond donors
2
H-bond acceptors
9
Rotatable bonds
5
Heavy atoms
32

SMILES CNCC1=CC(=NC=N1)OC2=CC3=C(C=C2)N(C=C3)C(=O)NC4=NN(C(=C4)C(F)(F)F)C

Computed descriptors from PubChem (CID 59394698), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.