Loading...
Chemical structure of Fezolinetant (ESN-364)

GC30104

Fezolinetant (ESN-364)

Also known as (4-fluorophenyl)-[(8R)-8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]methanone

Fezolinetant (ESN-364) is an antagonist of the neurokinin 3 receptor (NK3R), used for the treatment of menopausal hot flushes

ChemicalCAS1629229-37-3MW358.39FormulaC16H15FN6OS
CAS number
1629229-37-3
Molecular weight
358.39
Formula
C16H15FN6OS
Solubility
DMSO ： ≥ 50 mg/mL (139·51 mM)
InChIKey
PPSNFPASKFYPMN-SECBINFHSA-N
Catalogue number
GC30104
Brand
GLPBIO
Computed properties PubChem CID 117604931 · XLogP 1.6 · TPSA 105 Ų · H-bond donors 0
XLogP
1.6
TPSA
105 Ų
H-bond donors
0
H-bond acceptors
7
Rotatable bonds
2
Heavy atoms
25

SMILES C[C@@H]1C2=NN=C(N2CCN1C(=O)C3=CC=C(C=C3)F)C4=NC(=NS4)C

Computed descriptors from PubChem (CID 117604931), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.