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Chemical structure of Eleclazine hydrochloride

GC30063

Eleclazine hydrochloride

Also listed as Eleclazine hydrochloride (GS 6615 hydrochloride)

Eleclazine (GS 6615) hydrochloride is a selective cardiac late sodium current inhibitor and a weak inhibitor of potassium current with IC50 value of <1 μM and approximately 14·2 μM, respectively

ChemicalCAS1448754-43-5MW451.83FormulaC21H17ClF3N3O3
CAS number
1448754-43-5
Molecular weight
451.83
Formula
C21H17ClF3N3O3
Solubility
DMSO : ≥ 100 mg/mL (221·32 mM)
InChIKey
ZRYHNOXHGYUHFF-UHFFFAOYSA-N
Catalogue number
GC30063
Brand
GLPBIO
Computed properties PubChem CID 90479986 · TPSA 64.6 Ų · H-bond donors 1 · H-bond acceptors 8
TPSA
64.6 Ų
H-bond donors
1
H-bond acceptors
8
Rotatable bonds
4
Heavy atoms
31

SMILES C1COC2=C(C=C(C=C2)C3=CC=C(C=C3)OC(F)(F)F)C(=O)N1CC4=NC=CC=N4.Cl

Computed descriptors from PubChem (CID 90479986), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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Documents
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