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Chemical structure of (-)-Epipodophyllotoxin

GC26693

(-)-Epipodophyllotoxin

Also known as (5S,5aR,8aR,9R)-5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one

(-)-Epipodophyllotoxin (2) is an antiproliferative agent against cancer cells isolated from American mayapple Podophyllum peltatum, with GI50s of 0·36 and 0·24 μM in HeLa cells and MCF-7 cells, respectively

ChemicalCAS4375-07-9MW414.41FormulaC22H22O8
CAS number
4375-07-9
Molecular weight
414.41
Formula
C22H22O8
Solubility
DMSO ： ≥ 50 mg/mL (120·65 mM)
InChIKey
YJGVMLPVUAXIQN-LGWHJFRWSA-N
Catalogue number
GC26693
Brand
GLPBIO
Computed properties PubChem CID 105111 · XLogP 2 · TPSA 92.7 Ų · H-bond donors 1
XLogP
2
TPSA
92.7 Ų
H-bond donors
1
H-bond acceptors
8
Rotatable bonds
4
Heavy atoms
30

SMILES COC1=CC(=CC(=C1OC)OC)[C@H]2[C@@H]3[C@H](COC3=O)[C@@H](C4=CC5=C(C=C24)OCO5)O

Computed descriptors from PubChem (CID 105111), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.