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Chemical structure of Belumosudil mesylate

GC26330

Belumosudil mesylate

Also known as 2-[3-[5-(1H-indazol-5-ylamino)quinazolin-2-yl]phenoxy]-N-propan-2-ylacetamide;methanesulfonic acid

Belumosudil mesylate is a selective ROCK2 inhibitor, with IC50 values of 105nM for ROCK2 and 24µM for ROCK1

ChemicalCAS2109704-99-4MW548.61FormulaC27H28N6O5S
CAS number
2109704-99-4
Molecular weight
548.61
Formula
C27H28N6O5S
Solubility
DMSO : 12·5 mg/mL (22·78 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
InChIKey
BGNMZPDNJWWQCU-UHFFFAOYSA-N
Catalogue number
GC26330
Brand
GLPBIO
Computed properties PubChem CID 146025939 · TPSA 168 Ų · H-bond donors 4 · H-bond acceptors 9
TPSA
168 Ų
H-bond donors
4
H-bond acceptors
9
Rotatable bonds
7
Heavy atoms
39

SMILES CC(C)NC(=O)COC1=CC=CC(=C1)C2=NC=C3C(=N2)C=CC=C3NC4=CC5=C(C=C4)NN=C5.CS(=O)(=O)O

Computed descriptors from PubChem (CID 146025939), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.