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Chemical structure of conotoxin GI

GC26093

conotoxin GI

Also listed as α-Conotoxin GI

α-Conotoxin GI, a 13-residue peptide originally isolated from the venom of the fish-hunting cone snail Conus geographus, acts as a competitive antagonist for the muscle-type nicotinic acetylcholine receptor (nAChR) with excellent selectivity for α/δ receptor subunit binding over α/γ

ChemicalCAS76862-65-2MW1437.61FormulaC55H80N20O18S4
CAS number
76862-65-2
Molecular weight
1437.61
Formula
C55H80N20O18S4
Solubility
DMSO： 100 mg/mL (69·56 mM);Water： 50 mg/mL (34·78 mM);Ethanol： Insoluble
InChIKey
CSUQNJQRLCOOSR-NAKBKFBQSA-N
Catalogue number
GC26093
Brand
GLPBIO
Computed properties PubChem CID 25084484 · XLogP -10.1 · TPSA 725 Ų · H-bond donors 20
XLogP
-10.1
TPSA
725 Ų
H-bond donors
20
H-bond acceptors
25
Rotatable bonds
17
Heavy atoms
97

SMILES C[C@H]1C(=O)N[C@H]2CSSC[C@@H](C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CNC2=O)CCCN=C(N)N)CC3=CN=CN3)CC4=CC(=CC=C4)O)CO)C(=O)N)C(=O)N[C@H](C(=O)N5CCC[C@H]5C(=O)N1)CC(=O)N)NC(=O)[C@H](CCC(=O)O)N

Computed descriptors from PubChem (CID 25084484), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.