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Chemical structure of Perindopril arginine

GC25723

Perindopril arginine

Also listed as Perindopril L-Arginine

Perindopril L-Argininel is a prodrug that is metabolized in the liver to its active diacid metabolite perindoprilat, which is rapidly and extensively absorbed, and become one of the highest tissue angiotensin-converting enzyme (ACE) affinities among the ACE inhibitors

ChemicalCAS612548-45-5MW542.67FormulaC19H32N2O5·C6H14N4O2
CAS number
612548-45-5
Molecular weight
542.67
Formula
C19H32N2O5·C6H14N4O2
Solubility
DMSO: Insoluble;Water: 100 mg/mL (184·27 mM);Ethanol: 25 mg/mL (46·07 mM)
InChIKey
RYCSJJXKEWBUTI-YDYAIEMNSA-N
Catalogue number
GC25723
Brand
GLPBIO
Computed properties PubChem CID 12068809 · TPSA 224 Ų · H-bond donors 6 · H-bond acceptors 10
TPSA
224 Ų
H-bond donors
6
H-bond acceptors
10
Rotatable bonds
14
Heavy atoms
38

SMILES CCC[C@@H](C(=O)OCC)N[C@@H](C)C(=O)N1[C@H]2CCCC[C@H]2C[C@H]1C(=O)O.C(C[C@@H](C(=O)O)N)CN=C(N)N

Computed descriptors from PubChem (CID 12068809), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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