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Chemical structure of GJ103

GC25461

GJ103

Also known as 2-[[4-(3-methoxyphenyl)-5-pyridin-2-yl-1,2,4-triazol-3-yl]sulfanyl]acetic acid

GJ-103 is an active analog of GJ072 which is a read-through compound (RTC)· Chemical-induced read through of premature stop codons might be exploited as a potential treatment strategy for genetic disorders caused by nonsense mutations

ChemicalCAS1459687-89-8MW342.37FormulaC16H14N4O3S
CAS number
1459687-89-8
Molecular weight
342.37
Formula
C16H14N4O3S
Solubility
DMSO: 68 mg/mL (198·62 mM);Water: Insoluble;Ethanol: Insoluble
InChIKey
GBVQSAZHPCDBDY-UHFFFAOYSA-N
Catalogue number
GC25461
Brand
GLPBIO
Computed properties PubChem CID 71748051 · XLogP 2.1 · TPSA 115 Ų · H-bond donors 1
XLogP
2.1
TPSA
115 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
6
Heavy atoms
24

SMILES COC1=CC=CC(=C1)N2C(=NN=C2SCC(=O)O)C3=CC=CC=N3

Computed descriptors from PubChem (CID 71748051), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Documents
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