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Chemical structure of Dimethyl itaconate

GC25351

Dimethyl itaconate

Also known as dimethyl 2-methylidenebutanedioate

Dimethyl itaconate can reprogram neurotoxic to neuroprotective primary astrocytes through the regulation of LPS-induced Nod-like receptor protein 3 (NLRP3) inflammasome and nuclear factor 2/heme oxygenase-1 (NRF2/HO-1) pathways

ChemicalCAS617-52-7MW158.15FormulaC7H10O4
CAS number
617-52-7
Molecular weight
158.15
Formula
C7H10O4
Solubility
DMSO : 100 mg/mL (632·31 mM)
InChIKey
ZWWQRMFIZFPUAA-UHFFFAOYSA-N
Catalogue number
GC25351
Brand
GLPBIO
Computed properties PubChem CID 69240 · XLogP 0.5 · TPSA 52.6 Ų · H-bond donors 0
XLogP
0.5
TPSA
52.6 Ų
H-bond donors
0
H-bond acceptors
4
Rotatable bonds
5
Heavy atoms
11

SMILES COC(=O)CC(=C)C(=O)OC

Computed descriptors from PubChem (CID 69240), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.