GC25313
CS-2660 (JNJ-38158471)
Also known as 1-[4-[6-amino-5-[(E)-methoxyiminomethyl]pyrimidin-4-yl]oxy-2-chlorophenyl]-3-ethylurea
CS-2660 (JNJ-38158471) is a well tolerated, orally available, highly selective VEGFR-2 inhibitor with IC50 of 40 nM· CS-2660 (JNJ-38158471) also inhibits closely related tyrosine kinases such as RET (c-RET) and Kit (c-Kit) with IC50 of 180 nM and 500 nM,while it has no significant activity (>1 microM) against VEGFR-1 and VEGFR-3
ChemicalCAS951151-97-6MW364.79FormulaC15H17ClN6O3
- CAS number
- 951151-97-6
- Molecular weight
- 364.79
- Formula
- C15H17ClN6O3
- Solubility
- DMSO： 30 mg/mL (82·24 mM);Water： Insoluble;Ethanol： Insoluble
- InChIKey
- BJHCYTJNPVGSBZ-QPSGOUHRSA-N
- Catalogue number
- GC25313
- Brand
- GLPBIO
Computed properties PubChem CID 16742063 · XLogP 1.8 · TPSA 124 Ų · H-bond donors 3
- XLogP
- 1.8
- TPSA
- 124 Ų
- H-bond donors
- 3
- H-bond acceptors
- 7
- Rotatable bonds
- 6
- Heavy atoms
- 25
SMILES CCNC(=O)NC1=C(C=C(C=C1)OC2=NC=NC(=C2/C=N/OC)N)Cl
Computed descriptors from PubChem (CID 16742063), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il