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Chemical structure of Azvudine

GC25117

Azvudine

Also known as 4-amino-1-[(2R,3S,4R,5R)-5-azido-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one

Azvudine (RO-0622) is a novel nucleoside reverse transcriptase inhibitor with antiviral activity against human immunodeficiency virus (HIV), hepatitis B virus (HBV) and hepatitis C virus (HCV), potently inhibits HIV-1 (EC50 range 0·03 to 6·92 nM) and HIV-2 (EC50s ranging from 0·018 to 0·025 nM)

ChemicalCAS1011529-10-4MW286.22FormulaC9H11FN6O4
CAS number
1011529-10-4
Molecular weight
286.22
Formula
C9H11FN6O4
Solubility
DMSO： 57 mg/mL (199·15 mM);Water： 57 mg/mL (199·15 mM);Ethanol： 57 mg/mL (199·15 mM)
InChIKey
KTOLOIKYVCHRJW-XZMZPDFPSA-N
Catalogue number
GC25117
Brand
GLPBIO
Computed properties PubChem CID 24769759 · XLogP -0.8 · TPSA 123 Ų · H-bond donors 3
XLogP
-0.8
TPSA
123 Ų
H-bond donors
3
H-bond acceptors
7
Rotatable bonds
3
Heavy atoms
20

SMILES C1=CN(C(=O)N=C1N)[C@H]2[C@H]([C@@H]([C@](O2)(CO)N=[N+]=[N-])O)F

Computed descriptors from PubChem (CID 24769759), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.