Loading...
Chemical structure of AG-120 (racemic)

GC25039

AG-120 (racemic)

Also known as (2S)-N-[1-(2-chlorophenyl)-2-[(3,3-difluorocyclobutyl)amino]-2-oxoethyl]-1-(4-cyano-2-pyridinyl)-N-(5-fluoro-3-pyridinyl)-5-oxopyrrolidine-2-carboxamide

AG-120 (racemic), the racemic mixture of AG-120, is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1) with potential antineoplastic activity

ChemicalCAS1448346-63-1MW582.96FormulaC28H22ClF3N6O3
CAS number
1448346-63-1
Molecular weight
582.96
Formula
C28H22ClF3N6O3
Solubility
DMSO： 100 mg/mL (171·54 mM);Water： Insoluble;Ethanol： 100 mg/mL (171·54 mM)
InChIKey
WIJZXSAJMHAVGX-XADRRFQNSA-N
Catalogue number
GC25039
Brand
GLPBIO
Computed properties PubChem CID 89699486 · XLogP 3.4 · TPSA 119 Ų · H-bond donors 1
XLogP
3.4
TPSA
119 Ų
H-bond donors
1
H-bond acceptors
9
Rotatable bonds
7
Heavy atoms
41

SMILES C1CC(=O)N([C@@H]1C(=O)N(C2=CC(=CN=C2)F)C(C3=CC=CC=C3Cl)C(=O)NC4CC(C4)(F)F)C5=NC=CC(=C5)C#N

Computed descriptors from PubChem (CID 89699486), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.