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Chemical structure of CBR-470-1

GC19845

CBR-470-1

Also known as (3S,4R)-4-(4-chlorophenyl)sulfonyl-N-(2-methylpropyl)-1,1-dioxothiolan-3-amine

Cbr-470-1 is an inhibitor of glycolytic phosphoglycerate kinase 1 (PGK1)· Cbr-470-1 is also a non covalent Nrf2 activator· Cbr-470-1 protects SH-SY5Y neuronal cells from MPP + induced cytotoxicity by activating keap1-nrf2 cascade

ChemicalCAS2416095-06-0MW365.9FormulaC₁₄H₂₀ClNO₄S₂
CAS number
2416095-06-0
Molecular weight
365.9
Formula
C₁₄H₂₀ClNO₄S₂
Solubility
DMSO : 200 mg/mL (546·60 mM)
InChIKey
NFEQFEDSWINARK-KBPBESRZSA-N
Catalogue number
GC19845
Brand
GLPBIO
Computed properties PubChem CID 20898025 · XLogP 2.5 · TPSA 97.1 Ų · H-bond donors 1
XLogP
2.5
TPSA
97.1 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
5
Heavy atoms
22

SMILES CC(C)CN[C@H]1CS(=O)(=O)C[C@@H]1S(=O)(=O)C2=CC=C(C=C2)Cl

Computed descriptors from PubChem (CID 20898025), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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