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Chemical structure of Edicotinib

GC19418

Edicotinib

Also known as 5-cyano-N-[2-(4,4-dimethylcyclohexen-1-yl)-6-(2,2,6,6-tetramethyloxan-4-yl)-3-pyridinyl]-1H-imidazole-2-carboxamide

Edicotinib is a selective and orally available colony-stimulating factor-1 (CSF-1) receptor inhibitor, and has entered phase IIA clinical trial to study rheumatoid arthritis (RA) despite disease

ChemicalCAS1142363-52-7FormulaC27H35N5O2
CAS number
1142363-52-7
Molecular weight
Formula
C27H35N5O2
Solubility
DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7·2) (1:3): 0·25 mg/ml,Ethanol: 20 mg/ml
InChIKey
BNVPFDRNGHMRJS-UHFFFAOYSA-N
Catalogue number
GC19418
Brand
GLPBIO
Computed properties PubChem CID 25230468 · XLogP 4.3 · TPSA 104 Ų · H-bond donors 2
XLogP
4.3
TPSA
104 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
34

SMILES CC1(CCC(=CC1)C2=C(C=CC(=N2)C3CC(OC(C3)(C)C)(C)C)NC(=O)C4=NC=C(N4)C#N)C

Computed descriptors from PubChem (CID 25230468), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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