Loading...
Chemical structure of ABX-1431

GC19412

ABX-1431

Also known as 1,1,1,3,3,3-hexafluoropropan-2-yl 4-[[2-pyrrolidin-1-yl-4-(trifluoromethyl)phenyl]methyl]piperazine-1-carboxylate

ABX-1431 is a highly potent, selective, and orally available, CNS-penetrant monoacylglycerol lipase (MAGL) inhibitor with an IC50 of 14 nM

ChemicalCAS1446817-84-0FormulaC20H22F9N3O2
CAS number
1446817-84-0
Molecular weight
—
Formula
C20H22F9N3O2
Solubility
DMF： 10 mg/ml,DMSO： 10 mg/ml,Ethanol： 10 mg/ml,Ethanol：PBS (pH 7·2) (1：10)： 0·1 mg/ml
InChIKey
SQZJGTOZFRNWCX-UHFFFAOYSA-N
Catalogue number
GC19412
Brand
GLPBIO
Computed properties PubChem CID 71657619 · XLogP 5.2 · TPSA 36 Ų · H-bond donors 0
XLogP
5.2
TPSA
36 Ų
H-bond donors
0
H-bond acceptors
13
Rotatable bonds
5
Heavy atoms
34

SMILES C1CCN(C1)C2=C(C=CC(=C2)C(F)(F)F)CN3CCN(CC3)C(=O)OC(C(F)(F)F)C(F)(F)F

Computed descriptors from PubChem (CID 71657619), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.