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Chemical structure of IITZ-01

GC19411

IITZ-01

Also known as 4-N-[4-(1H-benzimidazol-2-yl)phenyl]-2-N-(4-fluorophenyl)-6-morpholin-4-yl-1,3,5-triazine-2,4-diamine

IITZ-01 is a potent lysosomotropic autophagy inhibitor with single-agent antitumor activity, with an IC50 of 2·62 μM for PI3Kγ

ChemicalCAS1807988-47-1FormulaC26H23FN8O
CAS number
1807988-47-1
Molecular weight
Formula
C26H23FN8O
Solubility
Soluble in DMSO
InChIKey
XGEDDGLPNSLBFE-UHFFFAOYSA-N
Catalogue number
GC19411
Brand
GLPBIO
Computed properties PubChem CID 134817273 · XLogP 5.2 · TPSA 104 Ų · H-bond donors 3
XLogP
5.2
TPSA
104 Ų
H-bond donors
3
H-bond acceptors
9
Rotatable bonds
6
Heavy atoms
36

SMILES C1COCCN1C2=NC(=NC(=N2)NC3=CC=C(C=C3)F)NC4=CC=C(C=C4)C5=NC6=CC=CC=C6N5

Computed descriptors from PubChem (CID 134817273), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.