Loading...
Chemical structure of FM381

GC19408

FM381

Also known as (E)-2-cyano-3-[5-(3-cyclohexyl-3,5,8,10-tetrazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaen-4-yl)furan-2-yl]-N,N-dimethylprop-2-enamide

FM-381 is a highly potent and JAK3-selective janus kinase (JAK) inhibitor

ChemicalCAS2226521-65-7MW428.496FormulaC24H24N6O2
CAS number
2226521-65-7
Molecular weight
428.496
Formula
C24H24N6O2
Solubility
DMSO： 2 mg/ml
InChIKey
GJMZWYLOARVASY-NTCAYCPXSA-N
Catalogue number
GC19408
Brand
GLPBIO
Computed properties PubChem CID 122197584 · XLogP 3.2 · TPSA 104 Ų · H-bond donors 1
XLogP
3.2
TPSA
104 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
32

SMILES CN(C)C(=O)/C(=C/C1=CC=C(O1)C2=NC3=CN=C4C(=C3N2C5CCCCC5)C=CN4)/C#N

Computed descriptors from PubChem (CID 122197584), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.