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Chemical structure of Mito-TRFS

GC19407

Mito-TRFS

Also known as 2-[2-[6-(dithiolan-4-yloxycarbonylamino)-1,3-dioxobenzo[de]isoquinolin-2-yl]ethoxy]ethyl-triphenylphosphanium iodide

Mito-TRFS is the first off-on probe for imaging the mitochondrial thioredoxin reductase (TrxR2) in live cells

ChemicalCAS1859102-62-7MW820.7FormulaC38H34IN2O5PS2
CAS number
1859102-62-7
Molecular weight
820.7
Formula
C38H34IN2O5PS2
Solubility
Soluble in DMSO
InChIKey
UKWAKZCQJRRDFN-UHFFFAOYSA-N
Catalogue number
GC19407
Brand
GLPBIO
Computed properties PubChem CID 154730958 · TPSA 136 Ų · H-bond donors 1 · H-bond acceptors 8
TPSA
136 Ų
H-bond donors
1
H-bond acceptors
8
Rotatable bonds
12
Heavy atoms
49

SMILES C1C(CSS1)OC(=O)NC2=C3C=CC=C4C3=C(C=C2)C(=O)N(C4=O)CCOCC[P+](C5=CC=CC=C5)(C6=CC=CC=C6)C7=CC=CC=C7.[I-]

Computed descriptors from PubChem (CID 154730958), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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