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Chemical structure of Upadacitinib

GC19368

Upadacitinib

Also known as (3S,4R)-3-ethyl-4-(1,5,7,10-tetrazatricyclo[7.3.0.02,6]dodeca-2(6),3,7,9,11-pentaen-12-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide

Upadacitinib is a highly potent, orally administered, and reversible selective Janus kinase 1 (JAK1) inhibitor with an IC50 value of 0·043μM

ChemicalCAS1310726-60-3MW380.37FormulaC17H19F3N6O
CAS number
1310726-60-3
Molecular weight
380.37
Formula
C17H19F3N6O
Solubility
DMSO ： ≥ 22 mg/mL (57·84 mM);Water ： ＜ 0·1 mg/mL (insoluble)
InChIKey
WYQFJHHDOKWSHR-MNOVXSKESA-N
Catalogue number
GC19368
Brand
GLPBIO
Computed properties PubChem CID 58557659 · XLogP 2.7 · TPSA 78.3 Ų · H-bond donors 2
XLogP
2.7
TPSA
78.3 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
3
Heavy atoms
27

SMILES CC[C@@H]1CN(C[C@@H]1C2=CN=C3N2C4=C(NC=C4)N=C3)C(=O)NCC(F)(F)F

Computed descriptors from PubChem (CID 58557659), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.