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Chemical structure of TAPI-2

GC19347

TAPI-2

Also known as N-[(2S)-1-[[(2S)-1-(2-aminoethylamino)-1-oxopropan-2-yl]amino]-3,3-dimethyl-1-oxobutan-2-yl]-N'-hydroxy-2-(2-methylpropyl)butanediamide

TAPI-2 is a broad-spectrum inhibitor of matrix metalloprotease (MMP), tumour necrosis factorα-converting enzyme (TACE) and a disintegrin and metalloproteinase (ADAM), with an IC50 of 20±10 uM for MMP

ChemicalCAS187034-31-7MW415.53FormulaC19H37N5O5
CAS number
187034-31-7
Molecular weight
415.53
Formula
C19H37N5O5
Solubility
DMSO ： ≥ 22 mg/mL (52·94 mM)
InChIKey
LMIQCBIEAHJAMZ-RMTCENKZSA-N
Catalogue number
GC19347
Brand
GLPBIO
Computed properties PubChem CID 10093303 · XLogP -0.1 · TPSA 163 Ų · H-bond donors 6
XLogP
-0.1
TPSA
163 Ų
H-bond donors
6
H-bond acceptors
6
Rotatable bonds
12
Heavy atoms
29

SMILES C[C@@H](C(=O)NCCN)NC(=O)[C@H](C(C)(C)C)NC(=O)C(CC(C)C)CC(=O)NO

Computed descriptors from PubChem (CID 10093303), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.