Loading...
Chemical structure of Solcitinib

GC19334

Solcitinib

Also known as N-[5-[4-(3,3-dimethylazetidine-1-carbonyl)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide

Solcitinib is an orally active, competitive, potent, selective JAK1 inhibitor, with an IC50 of 9·8 nM, and 11-, 55- and 23-fold selectivity over JAK2, JAK3 and TYK2, respectively; Solcitinib is used in the research of moderate-to-severe plaque-type psoriasis

ChemicalCAS1206163-45-2MW389.45FormulaC22H23N5O2
CAS number
1206163-45-2
Molecular weight
389.45
Formula
C22H23N5O2
Solubility
DMSO ： 20 mg/mL (51·35 mM)
InChIKey
MPYACSQFXVMWNO-UHFFFAOYSA-N
Catalogue number
GC19334
Brand
GLPBIO
Computed properties PubChem CID 44603362 · XLogP 2.8 · TPSA 79.6 Ų · H-bond donors 1
XLogP
2.8
TPSA
79.6 Ų
H-bond donors
1
H-bond acceptors
4
Rotatable bonds
4
Heavy atoms
29

SMILES CC1(CN(C1)C(=O)C2=CC=C(C=C2)C3=CC=CC4=NC(=NN43)NC(=O)C5CC5)C

Computed descriptors from PubChem (CID 44603362), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.