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Chemical structure of SB-649868

GC19323

SB-649868

Also known as N-[[(2S)-1-[5-(4-fluorophenyl)-2-methyl-1,3-thiazole-4-carbonyl]piperidin-2-yl]methyl]-1-benzofuran-4-carboxamide

SB-649868 is a potent and selective orally active orexin (OX) 1 and OX2 receptor antagonist (pKi =9·4 and 9·5 at the OX1 and OX2 receptor, respectively)

ChemicalCAS380899-24-1MW477.55FormulaC26H24FN3O3S
CAS number
380899-24-1
Molecular weight
477.55
Formula
C26H24FN3O3S
Solubility
DMF: 15mg/mL,DMF:PBS (pH 7·2) (1:20): 0·04mg/mL,DMSO: 10mg/mL,Ethanol: 0·3mg/mL
InChIKey
ZJXIUGNEAIHSBI-IBGZPJMESA-N
Catalogue number
GC19323
Brand
GLPBIO
Computed properties PubChem CID 25195495 · XLogP 5.2 · TPSA 104 Ų · H-bond donors 1
XLogP
5.2
TPSA
104 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
5
Heavy atoms
34

SMILES CC1=NC(=C(S1)C2=CC=C(C=C2)F)C(=O)N3CCCC[C@H]3CNC(=O)C4=C5C=COC5=CC=C4

Computed descriptors from PubChem (CID 25195495), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.