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Chemical structure of S49076

GC19317

S49076

Also known as 3-[[(3Z)-3-[[4-(morpholin-4-ylmethyl)-1H-pyrrol-2-yl]methylidene]-2-oxo-1H-indol-5-yl]methyl]-1,3-thiazolidine-2,4-dione

S49076 is a novel, potent inhibitor of MET, AXL/MER, and FGFR1/2/3 with IC50 values below 20 nM

ChemicalCAS1265965-22-7MW438.5FormulaC22H22N4O4S
CAS number
1265965-22-7
Molecular weight
438.5
Formula
C22H22N4O4S
Solubility
DMSO ： ≥ 31 mg/mL (70·70 mM)
InChIKey
AREYWCZYVPSHGS-NVMNQCDNSA-N
Catalogue number
GC19317
Brand
GLPBIO
Computed properties PubChem CID 49870909 · XLogP 1 · TPSA 120 Ų · H-bond donors 2
XLogP
1
TPSA
120 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
5
Heavy atoms
31

SMILES C1COCCN1CC2=CNC(=C2)/C=C\3/C4=C(C=CC(=C4)CN5C(=O)CSC5=O)NC3=O

Computed descriptors from PubChem (CID 49870909), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.