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Chemical structure of RAF709

GC19307

RAF709

Also known as N-[6-methyl-5-[5-morpholin-4-yl-6-(oxan-4-yloxy)-3-pyridinyl]-3-pyridinyl]-3-(trifluoromethyl)benzamide

RAF709 is a novel Raf kinase inhibitor extracted from patent WO2014151616A1, compound example 131, has an IC50 of 0·5 and 1·8 nM for c-Raf and b-Raf, respectively

ChemicalCAS1628838-42-5MW542.55FormulaC28H29F3N4O4
CAS number
1628838-42-5
Molecular weight
542.55
Formula
C28H29F3N4O4
Solubility
DMSO ： 100 mg/mL (184·31 mM)
InChIKey
FYNMINFUAIDIFL-UHFFFAOYSA-N
Catalogue number
GC19307
Brand
GLPBIO
Computed properties PubChem CID 90408826 · XLogP 4 · TPSA 85.8 Ų · H-bond donors 1
XLogP
4
TPSA
85.8 Ų
H-bond donors
1
H-bond acceptors
10
Rotatable bonds
6
Heavy atoms
39

SMILES CC1=C(C=C(C=N1)NC(=O)C2=CC(=CC=C2)C(F)(F)F)C3=CC(=C(N=C3)OC4CCOCC4)N5CCOCC5

Computed descriptors from PubChem (CID 90408826), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.