Loading...
Chemical structure of PFK-158

GC19293

PFK-158

Also known as (E)-1-pyridin-4-yl-3-[7-(trifluoromethyl)quinolin-2-yl]prop-2-en-1-one

PFK-158 is a potent and selective PFKFB3 inhibitor, which shows extensive anti-tumor activity by reducing the uptake of glucose in cancer cells, the production of ATP, the release of lactic acid and inducing apoptosis and autophagy

ChemicalCAS1462249-75-7MW328.29FormulaC18H11F3N2O
CAS number
1462249-75-7
Molecular weight
328.29
Formula
C18H11F3N2O
Solubility
DMSO ： ≥ 30 mg/mL (91·38 mM)
InChIKey
IAJOMYABKVAZCN-AATRIKPKSA-N
Catalogue number
GC19293
Brand
GLPBIO
Computed properties PubChem CID 71730058 · XLogP 3.8 · TPSA 42.9 Ų · H-bond donors 0
XLogP
3.8
TPSA
42.9 Ų
H-bond donors
0
H-bond acceptors
6
Rotatable bonds
3
Heavy atoms
24

SMILES C1=CC(=CC2=C1C=CC(=N2)/C=C/C(=O)C3=CC=NC=C3)C(F)(F)F

Computed descriptors from PubChem (CID 71730058), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.