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Chemical structure of Pemafibrate

GC19280

Pemafibrate

Also known as (2R)-2-[3-[[1,3-benzoxazol-2-yl-[3-(4-methoxyphenoxy)propyl]amino]methyl]phenoxy]butanoic acid

Pemafibrate (K-877) is an oral peroxisome proliferator-activated receptor (PPAR)-α agonist for the treatment of hyperlipidaemia, EC50 on Gal4hPPARα = 1 nM

ChemicalCAS848259-27-8MW490.55FormulaC28H30N2O6
CAS number
848259-27-8
Molecular weight
490.55
Formula
C28H30N2O6
Solubility
DMSO : ≥ 100 mg/mL (203·85 mM);Water : < 0·1 mg/mL (insoluble)
InChIKey
ZHKNLJLMDFQVHJ-RUZDIDTESA-N
Catalogue number
GC19280
Brand
GLPBIO
Computed properties PubChem CID 11526038 · XLogP 6.2 · TPSA 94.3 Ų · H-bond donors 1
XLogP
6.2
TPSA
94.3 Ų
H-bond donors
1
H-bond acceptors
8
Rotatable bonds
13
Heavy atoms
36

SMILES CC[C@H](C(=O)O)OC1=CC=CC(=C1)CN(CCCOC2=CC=C(C=C2)OC)C3=NC4=CC=CC=C4O3

Computed descriptors from PubChem (CID 11526038), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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