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Chemical structure of Paritaprevir

GC19275

Paritaprevir

Also known as (1S,4R,6S,7Z,14S,18R)-N-cyclopropylsulfonyl-14-[(5-methylpyrazine-2-carbonyl)amino]-2,15-dioxo-18-phenanthridin-6-yloxy-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide

Paritaprevir (ABT-450) is a potent non-structural protein 3/4A (NS3/4A) protease inhibitor with EC50s of 1 and 0·21 nM against HCV 1a and 1b, respectively

ChemicalCAS1216941-48-8MW765.88FormulaC40H43N7O7S
CAS number
1216941-48-8
Molecular weight
765.88
Formula
C40H43N7O7S
Solubility
DMSO ： ≥ 125 mg/mL (163·21 mM);Water ： ＜ 0·1 mg/mL (insoluble)
InChIKey
UAUIUKWPKRJZJV-QPLHLKROSA-N
Catalogue number
GC19275
Brand
GLPBIO
Computed properties PubChem CID 45110509 · XLogP 4.7 · TPSA 198 Ų · H-bond donors 3
XLogP
4.7
TPSA
198 Ų
H-bond donors
3
H-bond acceptors
10
Rotatable bonds
7
Heavy atoms
55

SMILES CC1=CN=C(C=N1)C(=O)N[C@H]2CCCCC/C=C\[C@@H]3C[C@]3(NC(=O)[C@@H]4C[C@H](CN4C2=O)OC5=NC6=CC=CC=C6C7=CC=CC=C75)C(=O)NS(=O)(=O)C8CC8

Computed descriptors from PubChem (CID 45110509), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.