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Chemical structure of LXH254

GC19228

LXH254

Also known as N-[3-[2-(2-hydroxyethoxy)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide

LXH254 is a potent CRAF inhibitor extracted from patent WO2018051306A1, Compound A

ChemicalCAS1800398-38-2MW502.49FormulaC25H25F3N4O4
CAS number
1800398-38-2
Molecular weight
502.49
Formula
C25H25F3N4O4
Solubility
DMSO ： ≥ 83·3 mg/mL (165·77 mM)
InChIKey
UEPXBTCUIIGYCY-UHFFFAOYSA-N
Catalogue number
GC19228
Brand
GLPBIO
Computed properties PubChem CID 90456533 · XLogP 3.2 · TPSA 96.8 Ų · H-bond donors 2
XLogP
3.2
TPSA
96.8 Ų
H-bond donors
2
H-bond acceptors
10
Rotatable bonds
7
Heavy atoms
36

SMILES CC1=C(C=C(C=C1)NC(=O)C2=CC(=NC=C2)C(F)(F)F)C3=CC(=NC(=C3)OCCO)N4CCOCC4

Computed descriptors from PubChem (CID 90456533), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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