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Chemical structure of LSZ-102

GC19224

LSZ-102

Also known as (E)-3-[4-[[2-[2-(1,1-difluoroethyl)-4-fluorophenyl]-6-hydroxy-1-benzothiophen-3-yl]oxy]phenyl]prop-2-enoic acid

LSZ-102 is a potent, orally bioavailable selective estrogen receptor degrader with an IC50 of 0·2 nM

ChemicalCAS2135600-76-7MW470.46FormulaC25H17F3O4S
CAS number
2135600-76-7
Molecular weight
470.46
Formula
C25H17F3O4S
Solubility
DMSO ： 100 mg/mL (212·56 mM; Need ultrasonic);Water ： ＜ 0·1 mg/mL (insoluble)
InChIKey
SJXNPGGVGZXKKI-NYYWCZLTSA-N
Catalogue number
GC19224
Brand
GLPBIO
Computed properties PubChem CID 118574930 · XLogP 6.6 · TPSA 95 Ų · H-bond donors 2
XLogP
6.6
TPSA
95 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
6
Heavy atoms
33

SMILES CC(C1=C(C=CC(=C1)F)C2=C(C3=C(S2)C=C(C=C3)O)OC4=CC=C(C=C4)/C=C/C(=O)O)(F)F

Computed descriptors from PubChem (CID 118574930), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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